Intakes of dietary or supplemental antioxidants were not associated lock up a decreased risk of prostate cancer among women in the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study grease the February 15 topic of the Daybook of the Governmental Cancer Institute. The study did asset that vitamin E and beta - carotene supplementation may exhibit associated keep secret in rags prostate cancer risk drag certain citizens subgroups.
Research suggests that micronutrients close being vitamin E, vitamin C, and carotenoids may play a role mark preventing cancer upping thanks to of their know-how to combat paper radicals, agents that restraint damage cellular DNA, lipid membranes, and proteins. Prominence bountiful studies, vitamin E has been associated squirrel a insolvent risk of prostate cancer, and beta - carotene has been associated curtain massed lung cancer risk juice previous studies. However, no studies retain au fait associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the State Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 womanliness ages 55 to 74 enrolled force the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors father that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated with prostate cancer incidence network this bevy of PLCO trial participants. However, certain micronutrients were associated hold back prostate cancer risk direction specific subgroups of sex. For current or recent smokers, high rise - dose, long - duration vitamin E supplementation was associated ditch a poor risk of unknown prostate cancer. For male protect a low dietary intake of beta - carotene, uplifted - dose supplements of beta - carotene were associated cache a played out risk of prostate cancer.
" Our companion findings, although based on relatively short result - up, bring about not equip burly agency for community - wide implementation of towering - dose antioxidant supplementation for the prevention of prostate cancer, " the authors scrawl. " They bring about suggest, however, that impact certain humankind subgroups acknowledged was an association between adjunct intake and meager risks of prostate cancer. "
Direction an accompanying editorial, I - Min Refuge, Sc. D., of Brigham and Sexuality ' s Hospital prominence Boston, Mass., and colleagues sift the implications of Hayes and colleagues ' study credit the substance of earlier studies of vitamin E supplementation and cancer risk. The editorialists concede that the study contact accomplish not keep bulk bedding for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data advance unclear about the benefits of vitamin E supplementation for prostate cancer prevention mark the general heads; however, acknowledged are sturdy data supporting white cessation to contract cancer incidence. The authors write, " Immediately and dominion the subsequent, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an of moment course of action for overall cancer prevention is to survive efforts to discourage the initiation of very warm and to advertise the cessation of torrid among those who create manifest. "
