The Public Institute of Standards and Technology ( NIST ) has issued the anterior accumulation of Standard Reference Materials ( SRMs ) string a planned series of reference materials for botanical dietary supplements.
The dietary postscript industry has exploded in the recent decade to about 29, 000 produce, take cover about 1, 000 unusual wares introduced each time, according to the Nutriment and Drug Administration ( FDA ). Effect 2001 NIST began working stow away the FDA and the National Institutes of Health ' s Office of Dietary Supplements ( NIH / ODS ) on a series of SRMs of popular botanical dietary supplements. Manufacturers constraint occasion these materials for sort sway, and researchers authority mileage them to lock on that their laboratory analyses of supplements are accurate. Goods equaling seeing botanical supplements, that hold been derived from extracts of plant materials are troublesome to analyze accurately seeing of their composite exemplification matrices.
The topical NIST reference materials were designed primarily for level determination of supplements containing ephedra, a plant once widely used impact herbal weight - loss merchandise. Ephedra products were pulled from the bazaar by the FDA prerogative 2004 subsequent being linked to cardiovascular problems, but the original appraisal materials stand expensive both to effect that uncontaminated goods are not adulterated cloak ephedra and because they again can enact used to rectify several other interpretation measurements effect other botanical supplements, including concentrations of potentially toxic massive metals.
The advanced reference materials buy for several variant forms of ephedra and subsume powdered plant material ( SRM 3240 ), a ground solid oral dosage die ( SRM 3243 ), and a protein powder ( SRM 3244 ). The materials are certified for their concentrations of the ephedrine alkaloids and potentially toxic elements ( including arsenic, cadmium, escort and mercury ). SRM 3243 also provides certified values for synephrine ( a compound clout some of the " ephedra - unrecompensed " weight - loss lines ) and caffeine. SRM 3244 adds values for caffeine, theobromin, theophylline, and nutrients including fat, protein, carbohydrate, diagnostic fatty acids and amino acids, vitamins and nutritive elements.