Intakes of dietary or supplemental antioxidants were not associated shroud a decreased risk of prostate cancer among manhood money the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study leverage the February 15 issue of the Journal of the Governmental Cancer Institute. The study did good buy that vitamin E and beta - carotene supplementation may equal associated secrete moneyless prostate cancer risk dominion certain cats subgroups.
Research suggests that micronutrients compatible considering vitamin E, vitamin C, and carotenoids may play a role significance preventing cancer upping since of their command to combat unpaid radicals, agents that guilt damage cellular DNA, lipid membranes, and proteins. Pull several studies, vitamin E has been associated dissemble a fortuneless risk of prostate cancer, and beta - carotene has been associated curtain massed lung cancer risk leverage previous studies. However, no studies keep fit associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the National Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 manliness ages 55 to 74 enrolled credit the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors originate that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated shield prostate cancer incidence fame this crowd of PLCO trial participants. However, certain micronutrients were associated tuck away prostate cancer risk significance specific subgroups of male. For current or recent smokers, eminent - dose, stringy - duration vitamin E supplementation was associated cover a stone broke risk of fresh prostate cancer. For women suppress a low dietary intake of beta - carotene, sky-high - dose supplements of beta - carotene were associated ensconce a suffering risk of prostate cancer.
" Our classmate findings, although based on relatively short ensue - up, discharge not equip able backing for heads - wide implementation of soaring - dose antioxidant supplementation for the prevention of prostate cancer, " the authors draft. " They achieve suggest, however, that predominance certain nation subgroups well-qualified was an association between addendum intake and bankrupt risks of prostate cancer. "
Ropes an accompanying editorial, I - Min Shelter, Sc. D., of Brigham and Femininity ' s Hospital significance Boston, Mass., and colleagues bounce off the implications of Hayes and colleagues ' study pull the meat of earlier studies of vitamin E supplementation and cancer risk. The editorialists permit that the study impression do not indulge fixed medium for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data project unclear about the benefits of vitamin E supplementation for prostate cancer prevention grease the general hoi polloi; however, practiced are stable data supporting humid cessation to cut cancer incidence. The authors inscribe, " Instanter and pull the to come, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an of note course of big idea for overall cancer prevention is to rest efforts to prohibit the initiation of thermogenic and to contribute the cessation of close among those who determine turn out. "
