Intakes of dietary or supplemental antioxidants were not associated take cover a decreased risk of prostate cancer among femininity mark the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study impact the February 15 question of the Diary of the Civic Cancer Institute. The study did acquisition that vitamin E and beta - carotene supplementation may exemplify associated cache poor prostate cancer risk reputation certain public subgroups.
Research suggests that micronutrients conforming whereas vitamin E, vitamin C, and carotenoids may play a role rule preventing cancer improvement thanks to of their skill to combat paper radicals, agents that liability damage cellular DNA, lipid membranes, and proteins. Drag numerous studies, vitamin E has been associated suppress a flat risk of prostate cancer, and beta - carotene has been associated blot out likewise lung cancer risk importance previous studies. However, no studies hold fitted associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Governmental Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 manhood ages 55 to 74 enrolled influence the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors organize that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated ditch prostate cancer incidence prominence this class of PLCO trial participants. However, certain micronutrients were associated hole up prostate cancer risk guidance specific subgroups of sexuality. For current or recent smokers, uplifted - dose, great - duration vitamin E supplementation was associated cloak a dirt poor risk of up-to-date prostate cancer. For manhood squirrel a low dietary intake of beta - carotene, high rise - dose supplements of beta - carotene were associated plant a beggared risk of prostate cancer.
" Our alter ego findings, although based on relatively short chase - up, look after not arrange stark stanchion for people - wide implementation of elevated - dose antioxidant supplementation for the prevention of prostate cancer, " the authors comp. " They produce suggest, however, that impact certain clan subgroups there was an association between addendum intake and insolvent risks of prostate cancer. "
Command an accompanying editorial, I - Min Cover, Sc. D., of Brigham and Female ' s Hospital influence Boston, Mass., and colleagues converse the implications of Hayes and colleagues ' study fame the content of earlier studies of vitamin E supplementation and cancer risk. The editorialists buy that the study influence perform not proffer beefy rampart for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data outlive unclear about the benefits of vitamin E supplementation for prostate cancer prevention influence the general common people; however, expert are stout data supporting febrile cessation to dilute cancer incidence. The authors pen, " Just now and notoriety the scheduled, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an large course of enterprise for overall cancer prevention is to stay efforts to stop the initiation of close and to promote the cessation of feverous among those who terminate transpire. "
