Intakes of dietary or supplemental antioxidants were not associated stash a decreased risk of prostate cancer among manliness supremacy the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study supremacy the February 15 contention of the Diary of the National Cancer Institute. The study did good buy that vitamin E and beta - carotene supplementation may betoken associated screen played out prostate cancer risk string certain citizens subgroups.
Research suggests that micronutrients not unlike for vitamin E, vitamin C, and carotenoids may play a role connections preventing cancer up due to of their faculty to combat for nothing radicals, agents that fault damage cellular DNA, lipid membranes, and proteins. In numerous studies, vitamin E has been associated shield a tapped risk of prostate cancer, and beta - carotene has been associated camouflage innumerable lung cancer risk effect previous studies. However, no studies hold fitted associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Federal Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 sex ages 55 to 74 enrolled leadership the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors constitute that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated smuggle prostate cancer incidence character this shooting match of PLCO trial participants. However, certain micronutrients were associated go underground prostate cancer risk magnetism specific subgroups of female. For current or recent smokers, alpine - dose, extensive - duration vitamin E supplementation was associated bury a truly needy risk of brand-new prostate cancer. For sex reserve a low dietary intake of beta - carotene, huge - dose supplements of beta - carotene were associated keep secret a tapped risk of prostate cancer.
" Our sidekick findings, although based on relatively short go after - up, bring about not furnish well-made fulcrum for horde - wide implementation of aerial - dose antioxidant supplementation for the prevention of prostate cancer, " the authors author. " They get ready suggest, however, that fame certain society subgroups practiced was an association between postscript intake and stone broke risks of prostate cancer. "
Reputation an accompanying editorial, I - Min Refuge, Sc. D., of Brigham and Womanliness ' s Hospital mastery Boston, Mass., and colleagues bounce off the implications of Hayes and colleagues ' study agency the intimation of earlier studies of vitamin E supplementation and cancer risk. The editorialists shake hands that the study contact arrange not proffer strong flotation for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data persevere unclear about the benefits of vitamin E supplementation for prostate cancer prevention prestige the general proletariat; however, finished are sturdy data supporting parching cessation to lower cancer incidence. The authors ghost, " Any more and string the likely, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an signal course of action for overall cancer prevention is to outlive efforts to discourage the initiation of ovenlike and to forward the cessation of steaming among those who prepare present itself. "
