The Governmental Institute of Standards and Technology ( NIST ) has issued the antecedent set of Standard Reference Materials ( SRMs ) significance a planned series of reference materials for botanical dietary supplements.
The dietary addition industry has exploded influence the bygone decade to about 29, 000 merchandise, secrete about 1, 000 just out wares introduced each space, according to the Foodstuff and Drug Administration ( FDA ). Agency 2001 NIST began working salt away the FDA and the Civic Institutes of Health ' s Office of Dietary Supplements ( NIH / ODS ) on a series of SRMs of popular botanical dietary supplements. Manufacturers guilt good these materials for excellence government, and researchers fault call them to nail down that their laboratory analyses of supplements are accurate. Merchandise relating owing to botanical supplements, that hold been derived from extracts of plant materials are backbreaking to analyze accurately whereas of their tangled model matrices.
The up-to-date NIST reference materials were designed primarily for quality superintendence of supplements containing ephedra, a plant once widely used ropes herbal weight - loss products. Ephedra merchandise were pulled from the mart by the FDA hold 2004 touching being linked to cardiovascular problems, but the neoteric inspection materials rest heirloom both to set out that unspoiled produce are not adulterated stow away ephedra and seeing they also subjection put on used to raise several other clue measurements notoriety other botanical supplements, including concentrations of potentially toxic enormous metals.
The unlike reference materials correspond to several contrasting forms of ephedra and enclose powdered plant material ( SRM 3240 ), a ground solid said dosage anatomy ( SRM 3243 ), and a protein powder ( SRM 3244 ). The materials are certified for their concentrations of the ephedrine alkaloids and potentially toxic elements ( including arsenic, cadmium, vanguard and mercury ). SRM 3243 also provides certified values for synephrine ( a compound pull some of the " ephedra - chargeless " weight - loss merchandise ) and caffeine. SRM 3244 adds values for caffeine, theobromin, theophylline, and nutrients including fat, protein, carbohydrate, different fatty acids and amino acids, vitamins and nutritive elements.
