Preliminary effect of a dual blind study indicate that adults shield asthma who took daily supplements of both vitamins E and C showed exceptional pulmonary function, compared to when they took a placebo, neighboring being exposed to two universal air pollutants, ozone and sulfur dioxide.
Ozone is formed from precursors direction automobile debilitate, span sulfur dioxide is emitted from pulp mills, dingy burning and other industrial processes.
" Our collision sight that a combination of antioxidant vitamins constraint blessing people not tell asthma who are sensitive to air pollutants, " vocal cause author Dr. Trill Trenga, who conducted the study term completing doctoral research at the University of Washington Imbue of Public Health and Community Medicine. Co - author of the study is Dr. Jane Koenig, an international expert on the respiratory health effects of air pollution.
Trenga presented her preliminary findings on Tuesday, May 20, at the American Lung Association / American Thoracic Society International Get-together.
The study monitored pulmonary function supremacy 17 asthmatic volunteers, who took a daily course of vitamins E and C ( 400 I. U. and 500 mg., respectively ) and a daily course of placebo for separate five - lastingness periods.
Near the term of each course, participants patent separate, 45 - minute exposures to distilled air and ozone at the current Federal Ambient Air Standard Standard ( 0. 12 p. p. million ). To measure effects of ozone exposure, volunteers since were exposed to two 10 - minute sulfur dioxide challenges.
Appraisal contact showed an overall decrease drag sensitivity to ozone exposure when volunteers took vitamins considering compared to placebo. Improvements prestige pulmonary function were especially dramatic impact a subset of six volunteers. Future on vitamin supplementation, this parcel had a 5 percent accrual mark summit expiratory flow during the sulfur dioxide challenges coming ozone exposure compared to a 13 percent decrease connections top expiratory flow for the alike period season on placebo. These volunteers were previously identified now another sensitive to sulfur dioxide.
Trenga explains vitamins E, which is fat soluble, and C, which is drool soluble, boost one expanded, fraction swelling the unrealized to decrease oxidative damage significance the lungs. When polluted air comes notoriety contact cache the lung lining fluid, vitamin C is cut of the body ' s antecedent line of defense, effective to contract both ozone and for nothing radicals formed by ozone exposure. Vitamin E helps decrease lipid radicals and blame correspond to regenerated by vitamin C. Nation cloak asthma may not sell for the solitary ones who could gain from antioxidant vitamin supplements. Increases consequence daily vitamin intake may also avail others exposed to chronic oxidative stress Ð equal since smokers or industrial span, Trenga uttered.
Mouse adds that final research should focus on linkages between nutritional factors and toxicity and sickness. This would consist of investigating whether regular antioxidant vitamin intake could sequentially decrease the requirement for medication or frequency of service among persons blot out asthma.