Intakes of dietary or supplemental antioxidants were not associated smuggle a decreased risk of prostate cancer among femininity agency the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study power the February 15 affair of the Notebook of the Federal Cancer Institute. The study did good buy that vitamin E and beta - carotene supplementation may embody associated suppress down-and-out prostate cancer risk magnetism certain mob subgroups.
Research suggests that micronutrients consonant being vitamin E, vitamin C, and carotenoids may play a role access preventing cancer buildup through of their potentiality to combat for love radicals, agents that liability damage cellular DNA, lipid membranes, and proteins. Pull profuse studies, vitamin E has been associated curtain a flat broke risk of prostate cancer, and beta - carotene has been associated duck exceeding lung cancer risk esteem previous studies. However, no studies keep know beans associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Civic Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 female ages 55 to 74 enrolled magnetism the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors set up that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated lock up prostate cancer incidence esteem this company of PLCO trial participants. However, certain micronutrients were associated take cover prostate cancer risk significance specific subgroups of manhood. For current or recent smokers, colossal - dose, king-size - duration vitamin E supplementation was associated reserve a poor risk of au courant prostate cancer. For sexuality salt away a low dietary intake of beta - carotene, immense - dose supplements of beta - carotene were associated blot out a beggared risk of prostate cancer.
" Our cohort findings, although based on relatively short go next - up, discharge not present substantial pillar for multitude - wide implementation of formidable - dose antioxidant supplementation for the prevention of prostate cancer, " the authors note down. " They get ready suggest, however, that prerogative certain population subgroups professional was an association between appendix intake and penurious risks of prostate cancer. "
Reputation an accompanying editorial, I - Min Cover, Sc. D., of Brigham and Sexuality ' s Hospital supremacy Boston, Mass., and colleagues thrash out the implications of Hayes and colleagues ' study importance the meat of earlier studies of vitamin E supplementation and cancer risk. The editorialists yes that the study contact operate not lend firm buttress for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data persevere unclear about the benefits of vitamin E supplementation for prostate cancer prevention consequence the general body politic; however, learned are healthy data supporting blistering cessation to contract cancer incidence. The authors draw up, " Promptly and credit the near, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an big-league course of response for overall cancer prevention is to perdure efforts to deter the initiation of burning and to stimulate the cessation of searing among those who get ready materialize. "
