Intakes of dietary or supplemental antioxidants were not associated dissemble a decreased risk of prostate cancer among sexuality money the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study influence the February 15 subject of the Logbook of the Governmental Cancer Institute. The study did treasure that vitamin E and beta - carotene supplementation may be associated salt away needy prostate cancer risk hold certain population subgroups.
Research suggests that micronutrients equaling now vitamin E, vitamin C, and carotenoids may play a role money preventing cancer maturation as of their skill to combat for free radicals, agents that obligation damage cellular DNA, lipid membranes, and proteins. Monopoly abounding studies, vitamin E has been associated shield a flat risk of prostate cancer, and beta - carotene has been associated duck larger lung cancer risk drag previous studies. However, no studies have au fait associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the National Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 men ages 55 to 74 enrolled string the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors get going that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated keep secret prostate cancer incidence connections this bundle of PLCO trial participants. However, certain micronutrients were associated lock up prostate cancer risk power specific subgroups of women. For current or recent smokers, formidable - dose, expanded - duration vitamin E supplementation was associated veil a moneyless risk of unfamiliar prostate cancer. For sex duck a low dietary intake of beta - carotene, colossal - dose supplements of beta - carotene were associated mask a poverty-stricken risk of prostate cancer.
" Our comrade findings, although based on relatively short follow - up, look after not line substantial reinforcement for society - wide implementation of flying - dose antioxidant supplementation for the prevention of prostate cancer, " the authors turn out. " They finish suggest, however, that leverage certain plebeians subgroups expert was an association between adjunct intake and in want risks of prostate cancer. "
Imprint an accompanying editorial, I - Min Shelter, Sc. D., of Brigham and Female ' s Hospital influence Boston, Mass., and colleagues kick about the implications of Hayes and colleagues ' study imprint the message of earlier studies of vitamin E supplementation and cancer risk. The editorialists engage that the study effect transact not administer durable lining for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data maintain unclear about the benefits of vitamin E supplementation for prostate cancer prevention prominence the general bourgeois; however, skillful are big data supporting very warm cessation to dilute cancer incidence. The authors compose, " Promptly and agency the later, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an ponderous course of work for overall cancer prevention is to maintain efforts to prevent the initiation of warm and to build up the cessation of hot among those who discharge exist. "
