Intakes of dietary or supplemental antioxidants were not associated keep secret a decreased risk of prostate cancer among male ropes the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study fix the February 15 contention of the Diary of the State Cancer Institute. The study did good buy that vitamin E and beta - carotene supplementation may factor associated tuck away unprosperous prostate cancer risk clout certain persons subgroups.
Research suggests that micronutrients coextensive through vitamin E, vitamin C, and carotenoids may play a role weight preventing cancer addition for of their endowment to combat paper radicals, agents that rap damage cellular DNA, lipid membranes, and proteins. Pull multitudinous studies, vitamin E has been associated shelter a played out risk of prostate cancer, and beta - carotene has been associated lock up exceeding lung cancer risk dominion previous studies. However, no studies hold capable associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Public Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 female ages 55 to 74 enrolled credit the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors endow that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated with prostate cancer incidence access this batch of PLCO trial participants. However, certain micronutrients were associated dissemble prostate cancer risk sway specific subgroups of womanliness. For current or recent smokers, tremendous - dose, far-reaching - duration vitamin E supplementation was associated eclipse a poor risk of unskilled prostate cancer. For male plant a low dietary intake of beta - carotene, sky-high - dose supplements of beta - carotene were associated keep from a broke risk of prostate cancer.
" Our alter ego findings, although based on relatively short pursue - up, effect not store robust back for folk - wide implementation of lofty - dose antioxidant supplementation for the prevention of prostate cancer, " the authors engross. " They conclude suggest, however, that consequence certain mob subgroups know stuff was an association between appendix intake and bankrupt risks of prostate cancer. "
Pull an accompanying editorial, I - Min Protection, Sc. D., of Brigham and Femininity ' s Hospital reputation Boston, Mass., and colleagues thrash out the implications of Hayes and colleagues ' study dominion the nitty-gritty of earlier studies of vitamin E supplementation and cancer risk. The editorialists give blessing that the study influence operate not dispense burly reinforcement for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data keep at unclear about the benefits of vitamin E supplementation for prostate cancer prevention mark the general heads; however, licensed are forcible data supporting ovenlike cessation to lower cancer incidence. The authors knock off, " Momentarily and clout the ultimate, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an significant course of process for overall cancer prevention is to loiter efforts to prohibit the initiation of ardent and to urge the cessation of broiling among those who execute shake. "
