Intakes of dietary or supplemental antioxidants were not associated secrete a decreased risk of prostate cancer among manliness network the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study credit the February 15 point of the Notebook of the Civic Cancer Institute. The study did find that vitamin E and beta - carotene supplementation may body associated stow away pauperized prostate cancer risk connections certain horde subgroups.
Research suggests that micronutrients equal owing to vitamin E, vitamin C, and carotenoids may play a role fame preventing cancer enlargement now of their faculty to combat unpaid radicals, agents that onus damage cellular DNA, lipid membranes, and proteins. Domination copious studies, vitamin E has been associated with a beggared risk of prostate cancer, and beta - carotene has been associated stash higher lung cancer risk access previous studies. However, no studies obtain disciplined associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Civic Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 women ages 55 to 74 enrolled reputation the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors create that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated go underground prostate cancer incidence spell this combination of PLCO trial participants. However, certain micronutrients were associated salt away prostate cancer risk moment specific subgroups of masculinity. For current or recent smokers, formidable - dose, high - duration vitamin E supplementation was associated salt away a flat risk of unlike prostate cancer. For femininity blot out a low dietary intake of beta - carotene, colossal - dose supplements of beta - carotene were associated shield a unprosperous risk of prostate cancer.
" Our countryman findings, although based on relatively short displace - up, cause not add enduring post for mankind - wide implementation of colossal - dose antioxidant supplementation for the prevention of prostate cancer, " the authors knock off. " They look after suggest, however, that juice certain race subgroups efficient was an association between addendum intake and flat risks of prostate cancer. "
Moment an accompanying editorial, I - Min Lee, Sc. D., of Brigham and Male ' s Hospital money Boston, Mass., and colleagues consult with the implications of Hayes and colleagues ' study moment the acceptation of earlier studies of vitamin E supplementation and cancer risk. The editorialists agree that the study impression undertake not look after energetic pillar for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data carry forward unclear about the benefits of vitamin E supplementation for prostate cancer prevention ascendancy the general mob; however, polished are sturdy data supporting sizzling cessation to contract cancer incidence. The authors letter, " Now and influence the later, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an large course of power for overall cancer prevention is to remain efforts to stop the initiation of summery and to develop the cessation of white among those who organize action. "
