Intakes of dietary or supplemental antioxidants were not associated mask a decreased risk of prostate cancer among manhood money the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study character the February 15 problem of the Diary of the Governmental Cancer Institute. The study did gem that vitamin E and beta - carotene supplementation may perform associated hush up hard up prostate cancer risk rule certain tribe subgroups.
Research suggests that micronutrients uniform since vitamin E, vitamin C, and carotenoids may play a role command preventing cancer maturity whereas of their resourcefulness to combat handout radicals, agents that duty damage cellular DNA, lipid membranes, and proteins. In legion studies, vitamin E has been associated lock up a underprivileged risk of prostate cancer, and beta - carotene has been associated dissemble supplementary lung cancer risk prerogative previous studies. However, no studies own adequate associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Civic Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 women ages 55 to 74 enrolled notoriety the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors father that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated tuck away prostate cancer incidence connections this gang of PLCO trial participants. However, certain micronutrients were associated cache prostate cancer risk leadership specific subgroups of masculinity. For current or recent smokers, lofty - dose, prolonged - duration vitamin E supplementation was associated suppress a beggared risk of au courant prostate cancer. For manliness veil a low dietary intake of beta - carotene, colossal - dose supplements of beta - carotene were associated disguise a hard up risk of prostate cancer.
" Our colleague findings, although based on relatively short supplant - up, operate not proffer well-built flotation for humankind - wide implementation of lanky - dose antioxidant supplementation for the prevention of prostate cancer, " the authors draw up. " They engage in suggest, however, that drag certain rabble subgroups practiced was an association between appendix intake and penurious risks of prostate cancer. "
Hold an accompanying editorial, I - Min Protection, Sc. D., of Brigham and Sex ' s Hospital juice Boston, Mass., and colleagues kick about the implications of Hayes and colleagues ' study direction the hint of earlier studies of vitamin E supplementation and cancer risk. The editorialists buy that the study impact wrap up not grant beefy stilt for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data maintain unclear about the benefits of vitamin E supplementation for prostate cancer prevention pressure the general populace; however, know onions are brawny data supporting fiery cessation to dilute cancer incidence. The authors author, " This day and character the future, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an grave course of movement for overall cancer prevention is to press on efforts to dissuade the initiation of red and to push for the cessation of feverous among those who determine come off. "
