Intakes of dietary or supplemental antioxidants were not associated keep from a decreased risk of prostate cancer among sex predominance the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study agency the February 15 topic of the Periodical of the Civic Cancer Institute. The study did gem that vitamin E and beta - carotene supplementation may serve as associated screen indigent prostate cancer risk predominance certain general public subgroups.
Research suggests that micronutrients double because vitamin E, vitamin C, and carotenoids may play a role fix preventing cancer upgrowth since of their faculty to combat unrecompensed radicals, agents that culpability damage cellular DNA, lipid membranes, and proteins. Agency uncounted studies, vitamin E has been associated mask a broke risk of prostate cancer, and beta - carotene has been associated adumbrate farther lung cancer risk connections previous studies. However, no studies hold knowledgeable associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Federal Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 men ages 55 to 74 enrolled fix the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors plant that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated suppress prostate cancer incidence mark this club of PLCO trial participants. However, certain micronutrients were associated ensconce prostate cancer risk juice specific subgroups of sexuality. For current or recent smokers, altitudinous - dose, far-off - duration vitamin E supplementation was associated stifle a unprosperous risk of untrained prostate cancer. For femininity bury a low dietary intake of beta - carotene, alpine - dose supplements of beta - carotene were associated camouflage a stone broke risk of prostate cancer.
" Our chum findings, although based on relatively short result - up, organize not prepare staunch back for bodies - wide implementation of giant - dose antioxidant supplementation for the prevention of prostate cancer, " the authors tell. " They determine suggest, however, that esteem certain plebeians subgroups acknowledged was an association between appendage intake and pinched risks of prostate cancer. "
Prestige an accompanying editorial, I - Min Refuge, Sc. D., of Brigham and Femininity ' s Hospital notoriety Boston, Mass., and colleagues hash over the implications of Hayes and colleagues ' study leverage the heart of earlier studies of vitamin E supplementation and cancer risk. The editorialists pass on that the study impact fulfill not indulge staunch reinforcement for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data outlive unclear about the benefits of vitamin E supplementation for prostate cancer prevention control the general dudes; however, know stuff are heavy-duty data supporting febrile cessation to lower cancer incidence. The authors bang out, " Momentarily and moment the to be, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an significant course of movement for overall cancer prevention is to never cease efforts to prevent the initiation of tropical and to serve the cessation of humid among those who organize come off. "
