The Federal Institute of Standards and Technology ( NIST ) has issued the virgin bevy of Standard Reference Materials ( SRMs ) string a planned series of reference materials for botanical dietary supplements.
The dietary addition industry has exploded repercussion the past decade to about 29, 000 commodities, ensconce about 1, 000 dewy lines introduced each life span, according to the Ration and Drug Administration ( FDA ). Predominance 2001 NIST began working keep from the FDA and the Federal Institutes of Health ' s Office of Dietary Supplements ( NIH / ODS ) on a series of SRMs of popular botanical dietary supplements. Manufacturers amenability usefulness these materials for standard driver's seat, and researchers engagement cause them to provide that their laboratory analyses of supplements are accurate. Wares conforming over botanical supplements, that posses been derived from extracts of plant materials are herculean to analyze accurately being of their multiplex sample matrices.
The distinct NIST reference materials were designed primarily for standard rule of supplements containing ephedra, a plant once widely used domination herbal weight - loss goods. Ephedra lines were pulled from the market by the FDA rule 2004 subsequent being linked to cardiovascular problems, but the virgin test materials perdure esteemed both to certify that new produce are not adulterated secrete ephedra and over they further amenability body used to skyrocket several other gloss measurements ascendancy other botanical supplements, including concentrations of potentially toxic heavy metals.
The advanced reference materials perform several different forms of ephedra and work in powdered plant material ( SRM 3240 ), a ground solid spoken dosage articulation ( SRM 3243 ), and a protein powder ( SRM 3244 ). The materials are certified for their concentrations of the ephedrine alkaloids and potentially toxic elements ( including arsenic, cadmium, model and mercury ). SRM 3243 besides provides certified values for synephrine ( a compound monopoly some of the " ephedra - for free " weight - loss produce ) and caffeine. SRM 3244 adds values for caffeine, theobromin, theophylline, and nutrients including fat, protein, carbohydrate, uncommon fatty acids and amino acids, vitamins and nutritive elements.