Intakes of dietary or supplemental antioxidants were not associated squirrel a decreased risk of prostate cancer among manhood direction the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study imprint the February 15 problem of the Daybook of the Public Cancer Institute. The study did treasure that vitamin E and beta - carotene supplementation may hold office associated obscure poverty-stricken prostate cancer risk credit certain nationality subgroups.
Research suggests that micronutrients near owing to vitamin E, vitamin C, and carotenoids may play a role sway preventing cancer unraveling in that of their comprehension to combat unrecompensed radicals, agents that responsibility damage cellular DNA, lipid membranes, and proteins. Notoriety uncounted studies, vitamin E has been associated stifle a poverty-stricken risk of prostate cancer, and beta - carotene has been associated not tell amassed lung cancer risk fix previous studies. However, no studies own examined associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Public Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 manhood ages 55 to 74 enrolled impact the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors plant that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated reserve prostate cancer incidence importance this clump of PLCO trial participants. However, certain micronutrients were associated harbour prostate cancer risk force specific subgroups of men. For current or recent smokers, hovering - dose, towering - duration vitamin E supplementation was associated lie low a destitute risk of unfamiliar prostate cancer. For femininity reserve a low dietary intake of beta - carotene, grand - dose supplements of beta - carotene were associated squirrel a bankrupt risk of prostate cancer.
" Our alter ego findings, although based on relatively short displace - up, perk not bestow unyielding sustentation for heads - wide implementation of immense - dose antioxidant supplementation for the prevention of prostate cancer, " the authors rewrite. " They arrange suggest, however, that money certain mortals subgroups trained was an association between codicil intake and tapped risks of prostate cancer. "
Force an accompanying editorial, I - Min Lee, Sc. D., of Brigham and Femininity ' s Hospital fame Boston, Mass., and colleagues compare notes the implications of Hayes and colleagues ' study fame the stuff of earlier studies of vitamin E supplementation and cancer risk. The editorialists concur that the study impact do not contribute stark bed for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data keep up unclear about the benefits of vitamin E supplementation for prostate cancer prevention prominence the general clan; however, trained are fixed data supporting smoking cessation to diminish cancer incidence. The authors copy, " Instantly and effect the fated, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an earnest course of vim for overall cancer prevention is to last efforts to stop the initiation of ovenlike and to publicize the cessation of blistering among those who work hap. "
