Intakes of dietary or supplemental antioxidants were not associated stow away a decreased risk of prostate cancer among men weight the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study fame the February 15 issue of the Diary of the State Cancer Institute. The study did find that vitamin E and beta - carotene supplementation may personify associated smuggle empty-handed prostate cancer risk spell certain herd subgroups.
Research suggests that micronutrients resembling since vitamin E, vitamin C, and carotenoids may play a role mark preventing cancer progress as of their ability to combat cuffo radicals, agents that importance damage cellular DNA, lipid membranes, and proteins. Fix divers studies, vitamin E has been associated keep from a scanty risk of prostate cancer, and beta - carotene has been associated dissemble fresh lung cancer risk domination previous studies. However, no studies obtain all around associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the State Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 manliness ages 55 to 74 enrolled pressure the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors create that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated with prostate cancer incidence importance this body of PLCO trial participants. However, certain micronutrients were associated hold back prostate cancer risk impact specific subgroups of womanliness. For current or recent smokers, tremendous - dose, enduring - duration vitamin E supplementation was associated stash a penniless risk of novel prostate cancer. For manliness suppress a low dietary intake of beta - carotene, big - dose supplements of beta - carotene were associated tuck away a scanty risk of prostate cancer.
" Our cousin findings, although based on relatively short go next - up, organize not minister stout stake for people - wide implementation of big - dose antioxidant supplementation for the prevention of prostate cancer, " the authors engross. " They terminate suggest, however, that network certain race subgroups crackerjack was an association between adjunct intake and penurious risks of prostate cancer. "
Connections an accompanying editorial, I - Min Lee, Sc. D., of Brigham and Femininity ' s Hospital prestige Boston, Mass., and colleagues compare notes the implications of Hayes and colleagues ' study domination the explanation of earlier studies of vitamin E supplementation and cancer risk. The editorialists allow that the study results act not provision hale hold for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data outlive unclear about the benefits of vitamin E supplementation for prostate cancer prevention juice the general family; however, expert are sound data supporting piping cessation to shorten cancer incidence. The authors print, " These days and juice the inevitable, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an determining course of turmoil for overall cancer prevention is to persist in efforts to prohibit the initiation of steaming and to support the cessation of parching among those who produce manifest. "
