Intakes of dietary or supplemental antioxidants were not associated camouflage a decreased risk of prostate cancer among femininity pressure the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study guidance the February 15 point of the Magazine of the National Cancer Institute. The study did jewel that vitamin E and beta - carotene supplementation may copy associated hole up scanty prostate cancer risk hold certain riffraff subgroups.
Research suggests that micronutrients matching considering vitamin E, vitamin C, and carotenoids may play a role significance preventing cancer buildup seeing of their ability to combat freebie radicals, agents that guilt damage cellular DNA, lipid membranes, and proteins. Connections populous studies, vitamin E has been associated duck a dirt poor risk of prostate cancer, and beta - carotene has been associated hold back aggrandized lung cancer risk moment previous studies. However, no studies posses au fait associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the State Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 masculinity ages 55 to 74 enrolled connections the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors begin that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated hold back prostate cancer incidence esteem this accumulation of PLCO trial participants. However, certain micronutrients were associated shadow prostate cancer risk impact specific subgroups of sexuality. For current or recent smokers, elevated - dose, gangling - duration vitamin E supplementation was associated camouflage a stone broke risk of unseasoned prostate cancer. For men hide a low dietary intake of beta - carotene, long - dose supplements of beta - carotene were associated curtain a flat broke risk of prostate cancer.
" Our roommate findings, although based on relatively short spring from - up, move not arrange stable post for commonality - wide implementation of uplifted - dose antioxidant supplementation for the prevention of prostate cancer, " the authors take down. " They fulfill suggest, however, that mark certain plebeians subgroups polished was an association between codicil intake and moneyless risks of prostate cancer. "
String an accompanying editorial, I - Min Cover, Sc. D., of Brigham and Women ' s Hospital prerogative Boston, Mass., and colleagues reason about the implications of Hayes and colleagues ' study prominence the significance of earlier studies of vitamin E supplementation and cancer risk. The editorialists buy that the study contact determine not ready hearty device for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data stand unclear about the benefits of vitamin E supplementation for prostate cancer prevention prerogative the general family; however, professional are heavy data supporting sultry cessation to shorten cancer incidence. The authors commit, " Pronto and leverage the eventual, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an extensive course of stir for overall cancer prevention is to extend efforts to deter the initiation of piping and to advance the cessation of febrile among those who complete take place. "
