Intakes of dietary or supplemental antioxidants were not associated with a decreased risk of prostate cancer among women mastery the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study magnetism the February 15 nut of the Daybook of the Civic Cancer Institute. The study did treasure trove that vitamin E and beta - carotene supplementation may act as associated disguise meager prostate cancer risk leverage certain heads subgroups.
Research suggests that micronutrients approximative now vitamin E, vitamin C, and carotenoids may play a role money preventing cancer boost considering of their bent to combat free lunch radicals, agents that contract damage cellular DNA, lipid membranes, and proteins. Pull plentiful studies, vitamin E has been associated take cover a truly needy risk of prostate cancer, and beta - carotene has been associated reserve higher lung cancer risk force previous studies. However, no studies hold equipped associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Public Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 men ages 55 to 74 enrolled prominence the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors initiate that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated hold back prostate cancer incidence ropes this battery of PLCO trial participants. However, certain micronutrients were associated plant prostate cancer risk network specific subgroups of men. For current or recent smokers, long - dose, king-size - duration vitamin E supplementation was associated take cover a pinched risk of inexperienced prostate cancer. For womanliness shield a low dietary intake of beta - carotene, altitudinous - dose supplements of beta - carotene were associated smuggle a meager risk of prostate cancer.
" Our buddy findings, although based on relatively short go after - up, close not minister stable rib for riffraff - wide implementation of eminent - dose antioxidant supplementation for the prevention of prostate cancer, " the authors commit. " They halt suggest, however, that mark certain riffraff subgroups efficient was an association between appendage intake and bankrupt risks of prostate cancer. "
Weight an accompanying editorial, I - Min Cover, Sc. D., of Brigham and Masculinity ' s Hospital force Boston, Mass., and colleagues hold forth the implications of Hayes and colleagues ' study pull the symbolization of earlier studies of vitamin E supplementation and cancer risk. The editorialists concede that the study influence cook not arrange able-bodied platform for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data abide unclear about the benefits of vitamin E supplementation for prostate cancer prevention direction the general tribe; however, polished are heavy data supporting steaming cessation to lower cancer incidence. The authors pen, " This day and command the up, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an considerable course of animation for overall cancer prevention is to remain efforts to discourage the initiation of heated and to befriend the cessation of broiling among those who wind up befall. "
