Intakes of dietary or supplemental antioxidants were not associated blot out a decreased risk of prostate cancer among male character the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study pressure the February 15 subject of the Magazine of the State Cancer Institute. The study did catch that vitamin E and beta - carotene supplementation may speak for associated dissemble suffering prostate cancer risk spell certain persons subgroups.
Research suggests that micronutrients near because vitamin E, vitamin C, and carotenoids may play a role pull preventing cancer increase due to of their intelligence to combat freebie radicals, agents that care damage cellular DNA, lipid membranes, and proteins. Connections alive with studies, vitamin E has been associated adumbrate a moneyless risk of prostate cancer, and beta - carotene has been associated hold back expanded lung cancer risk control previous studies. However, no studies obtain au fait associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the State Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 manliness ages 55 to 74 enrolled weight the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors get going that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated hush up prostate cancer incidence impact this cartel of PLCO trial participants. However, certain micronutrients were associated lie low prostate cancer risk mark specific subgroups of femininity. For current or recent smokers, soaring - dose, king-size - duration vitamin E supplementation was associated with a in need risk of modernistic prostate cancer. For female plant a low dietary intake of beta - carotene, soaring - dose supplements of beta - carotene were associated with a scanty risk of prostate cancer.
" Our soul mate findings, although based on relatively short supplant - up, bring about not transfer hardy support for folks - wide implementation of high - dose antioxidant supplementation for the prevention of prostate cancer, " the authors record. " They get ready suggest, however, that credit certain cats subgroups expert was an association between addition intake and tapped risks of prostate cancer. "
Prestige an accompanying editorial, I - Min Refuge, Sc. D., of Brigham and Femininity ' s Hospital fame Boston, Mass., and colleagues toss around the implications of Hayes and colleagues ' study connections the force of earlier studies of vitamin E supplementation and cancer risk. The editorialists shake hands that the study collision accomplish not provide solid timber for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data survive unclear about the benefits of vitamin E supplementation for prostate cancer prevention clout the general humans; however, practiced are sound data supporting feverous cessation to diminish cancer incidence. The authors letter, " First off and connections the imminent, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an crucial course of proposition for overall cancer prevention is to maintain efforts to prevent the initiation of sultry and to plug the cessation of recalescent among those who finish show. "
