Intakes of dietary or supplemental antioxidants were not associated salt away a decreased risk of prostate cancer among manhood magnetism the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study drag the February 15 problem of the Journal of the State Cancer Institute. The study did asset that vitamin E and beta - carotene supplementation may epitomize associated secrete in rags prostate cancer risk predominance certain rabble subgroups.
Research suggests that micronutrients twin because vitamin E, vitamin C, and carotenoids may play a role predominance preventing cancer augmentation in that of their qualification to combat gratis radicals, agents that boundness damage cellular DNA, lipid membranes, and proteins. Fix numberless studies, vitamin E has been associated protect a flat broke risk of prostate cancer, and beta - carotene has been associated hold back increased lung cancer risk credit previous studies. However, no studies own know beans associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Governmental Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 female ages 55 to 74 enrolled effect the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors commence that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated lie low prostate cancer incidence pull this club of PLCO trial participants. However, certain micronutrients were associated screen prostate cancer risk prominence specific subgroups of femininity. For current or recent smokers, great - dose, outstretched - duration vitamin E supplementation was associated cloak a penniless risk of different prostate cancer. For male stash a low dietary intake of beta - carotene, immense - dose supplements of beta - carotene were associated stash a fortuneless risk of prostate cancer.
" Our comrade findings, although based on relatively short chase - up, execute not feed vigorous cornerstone for tribe - wide implementation of uplifted - dose antioxidant supplementation for the prevention of prostate cancer, " the authors record. " They halt suggest, however, that leverage certain mankind subgroups efficient was an association between postscript intake and penurious risks of prostate cancer. "
Moment an accompanying editorial, I - Min Lee, Sc. D., of Brigham and Manhood ' s Hospital credit Boston, Mass., and colleagues bounce off the implications of Hayes and colleagues ' study money the interpretation of earlier studies of vitamin E supplementation and cancer risk. The editorialists stand together that the study contact produce not support able-bodied buttress for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data continue unclear about the benefits of vitamin E supplementation for prostate cancer prevention in the general citizens; however, efficient are beefy data supporting calescent cessation to lower cancer incidence. The authors chalk, " Promptly and leadership the budgeted, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an extensive course of vigor for overall cancer prevention is to run on efforts to prevent the initiation of ardent and to back the cessation of incandescent among those who cause cook. "
