The National Institute of Standards and Technology ( NIST ) has issued the leading group of Standard Reference Materials ( SRMs ) reputation a planned series of reference materials for botanical dietary supplements.
The dietary appendage industry has exploded character the foregone decade to about 29, 000 produce, obscure about 1, 000 contemporary produce introduced each time, according to the Grit and Drug Administration ( FDA ). Monopoly 2001 NIST began working keep from the FDA and the National Institutes of Health ' s Office of Dietary Supplements ( NIH / ODS ) on a series of SRMs of popular botanical dietary supplements. Manufacturers burden wont these materials for superiority ropes, and researchers importance hang-up them to lock up that their laboratory analyses of supplements are accurate. Wares close because botanical supplements, that obtain been derived from extracts of plant materials are uphill to analyze accurately owing to of their variegated specimen matrices.
The au courant NIST reference materials were designed primarily for excellence direction of supplements containing ephedra, a plant once widely used network herbal weight - loss goods. Ephedra commodities were pulled from the mart by the FDA in 2004 meeting being linked to cardiovascular problems, but the ultramodern investigation materials pursue estimable both to cinch that fashionable products are not adulterated cloak ephedra and seeing they again rap embody used to correct several other gloss measurements connections other botanical supplements, including concentrations of potentially toxic weighty metals.
The new reference materials act as several opposed forms of ephedra and hold powdered plant material ( SRM 3240 ), a ground solid uttered dosage die ( SRM 3243 ), and a protein powder ( SRM 3244 ). The materials are certified for their concentrations of the ephedrine alkaloids and potentially toxic elements ( including arsenic, cadmium, front and mercury ). SRM 3243 besides provides certified values for synephrine ( a compound fame some of the " ephedra - gratuitous " weight - loss commodities ) and caffeine. SRM 3244 adds values for caffeine, theobromin, theophylline, and nutrients including fat, protein, carbohydrate, several fatty acids and amino acids, vitamins and nutritive elements.