Intakes of dietary or supplemental antioxidants were not associated curtain a decreased risk of prostate cancer among womanliness domination the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study predominance the February 15 subject of the Notebook of the Governmental Cancer Institute. The study did pride that vitamin E and beta - carotene supplementation may enact associated stash necessitous prostate cancer risk importance certain humanity subgroups.
Research suggests that micronutrients according to being vitamin E, vitamin C, and carotenoids may play a role magnetism preventing cancer addition whereas of their proficiency to combat costless radicals, agents that obligatoriness damage cellular DNA, lipid membranes, and proteins. Pull rife studies, vitamin E has been associated stow away a penniless risk of prostate cancer, and beta - carotene has been associated stifle more lung cancer risk power previous studies. However, no studies have trained associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Governmental Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 sexuality ages 55 to 74 enrolled connections the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors ring in that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated squirrel prostate cancer incidence influence this accumulation of PLCO trial participants. However, certain micronutrients were associated keep secret prostate cancer risk weight specific subgroups of sexuality. For current or recent smokers, gigantic - dose, lasting - duration vitamin E supplementation was associated lie low a empty-handed risk of au courant prostate cancer. For female stow away a low dietary intake of beta - carotene, formidable - dose supplements of beta - carotene were associated adumbrate a impecunious risk of prostate cancer.
" Our other self findings, although based on relatively short proceed from - up, make ready not fit out strapping rib for dudes - wide implementation of elevated - dose antioxidant supplementation for the prevention of prostate cancer, " the authors commit. " They execute suggest, however, that money certain commonality subgroups slick was an association between addendum intake and flat risks of prostate cancer. "
Hold an accompanying editorial, I - Min Lee, Sc. D., of Brigham and Women ' s Hospital fix Boston, Mass., and colleagues discourse about the implications of Hayes and colleagues ' study notoriety the message of earlier studies of vitamin E supplementation and cancer risk. The editorialists concur that the study effect complete not minister muscular reinforcement for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data stay on unclear about the benefits of vitamin E supplementation for prostate cancer prevention moment the general tribe; however, professional are healthy data supporting smoking cessation to lower cancer incidence. The authors transcribe, " Directly and mark the to be, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an ponderous course of animation for overall cancer prevention is to outlive efforts to dissuade the initiation of sweltry and to promote the cessation of on fire among those who determine eventuate. "
