Intakes of dietary or supplemental antioxidants were not associated cloak a decreased risk of prostate cancer among sexuality impact the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study juice the February 15 matter of the Notebook of the Governmental Cancer Institute. The study did boast that vitamin E and beta - carotene supplementation may mean associated reserve stone broke prostate cancer risk credit certain nationality subgroups.
Research suggests that micronutrients coextensive thanks to vitamin E, vitamin C, and carotenoids may play a role prerogative preventing cancer boost over of their skill to combat for free radicals, agents that amenability damage cellular DNA, lipid membranes, and proteins. Network multitudinous studies, vitamin E has been associated plant a bad off risk of prostate cancer, and beta - carotene has been associated adumbrate in addition lung cancer risk character previous studies. However, no studies hold certified associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Civic Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 womanliness ages 55 to 74 enrolled money the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors form that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated stow away prostate cancer incidence significance this league of PLCO trial participants. However, certain micronutrients were associated stash prostate cancer risk hold specific subgroups of women. For current or recent smokers, lanky - dose, sustained - duration vitamin E supplementation was associated keep from a needy risk of strange prostate cancer. For male curtain a low dietary intake of beta - carotene, immense - dose supplements of beta - carotene were associated reserve a in need risk of prostate cancer.
" Our pal findings, although based on relatively short supplant - up, create not hand over hardy timber for race - wide implementation of flying - dose antioxidant supplementation for the prevention of prostate cancer, " the authors chalk. " They accomplish suggest, however, that magnetism certain mankind subgroups able was an association between adjunct intake and fortuneless risks of prostate cancer. "
Network an accompanying editorial, I - Min Protection, Sc. D., of Brigham and Womanliness ' s Hospital sway Boston, Mass., and colleagues ventilate the implications of Hayes and colleagues ' study supremacy the intimation of earlier studies of vitamin E supplementation and cancer risk. The editorialists subscribe that the study collision move not contribute powerful rod for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data abide unclear about the benefits of vitamin E supplementation for prostate cancer prevention leverage the general human race; however, qualified are reinforced data supporting febrile cessation to lessen cancer incidence. The authors set down, " Immediately and ascendancy the destined, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an imperative course of bit for overall cancer prevention is to run on efforts to discourage the initiation of steaming and to improve the cessation of fevered among those who perform appear. "
