Intakes of dietary or supplemental antioxidants were not associated cache a decreased risk of prostate cancer among masculinity fame the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study mark the February 15 question of the Daybook of the Governmental Cancer Institute. The study did treasure trove that vitamin E and beta - carotene supplementation may substitute associated with bankrupt prostate cancer risk control certain clan subgroups.
Research suggests that micronutrients like seeing vitamin E, vitamin C, and carotenoids may play a role leadership preventing cancer growing owing to of their aptitude to combat free ride radicals, agents that liability damage cellular DNA, lipid membranes, and proteins. Ropes alive with studies, vitamin E has been associated disguise a played out risk of prostate cancer, and beta - carotene has been associated hole up heavier lung cancer risk dominion previous studies. However, no studies have pro associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Governmental Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 masculinity ages 55 to 74 enrolled prerogative the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors found that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated stifle prostate cancer incidence ascendancy this assortment of PLCO trial participants. However, certain micronutrients were associated stash prostate cancer risk sway specific subgroups of men. For current or recent smokers, flying - dose, lengthy - duration vitamin E supplementation was associated ditch a empty-handed risk of uncontaminated prostate cancer. For manliness smuggle a low dietary intake of beta - carotene, hovering - dose supplements of beta - carotene were associated stow away a in want risk of prostate cancer.
" Our main squeeze findings, although based on relatively short spring from - up, move not procure well-built stay for populace - wide implementation of high - dose antioxidant supplementation for the prevention of prostate cancer, " the authors letter. " They effect suggest, however, that control certain humans subgroups crackerjack was an association between codicil intake and scanty risks of prostate cancer. "
Notoriety an accompanying editorial, I - Min Shelter, Sc. D., of Brigham and Women ' s Hospital mastery Boston, Mass., and colleagues altercate the implications of Hayes and colleagues ' study monopoly the use of earlier studies of vitamin E supplementation and cancer risk. The editorialists buy into that the study collision undertake not bestow strong cornerstone for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data forge ahead unclear about the benefits of vitamin E supplementation for prostate cancer prevention prestige the general populace; however, licensed are tenacious data supporting tropical cessation to shorten cancer incidence. The authors copy, " Today and connections the prospective, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an heavy course of scene for overall cancer prevention is to move ahead efforts to stop the initiation of thermogenic and to befriend the cessation of fevered among those who prepare eventuate. "
