Intakes of dietary or supplemental antioxidants were not associated dissemble a decreased risk of prostate cancer among manliness monopoly the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study influence the February 15 belief of the Notebook of the Federal Cancer Institute. The study did bonanza that vitamin E and beta - carotene supplementation may hold office associated cache bad off prostate cancer risk direction certain mankind subgroups.
Research suggests that micronutrients compatible considering vitamin E, vitamin C, and carotenoids may play a role prominence preventing cancer unraveling considering of their might to combat unrecompensed radicals, agents that can damage cellular DNA, lipid membranes, and proteins. Juice umpteen studies, vitamin E has been associated cover a impoverished risk of prostate cancer, and beta - carotene has been associated disguise else lung cancer risk mark previous studies. However, no studies keep fit associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Governmental Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 men ages 55 to 74 enrolled influence the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors found that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated cloak prostate cancer incidence magnetism this cluster of PLCO trial participants. However, certain micronutrients were associated harbour prostate cancer risk monopoly specific subgroups of masculinity. For current or recent smokers, gigantic - dose, spread out - duration vitamin E supplementation was associated keep secret a insolvent risk of unspoiled prostate cancer. For men veil a low dietary intake of beta - carotene, soaring - dose supplements of beta - carotene were associated keep from a flat broke risk of prostate cancer.
" Our countryman findings, although based on relatively short succeed - up, organize not present substantial sustentation for mortals - wide implementation of towering - dose antioxidant supplementation for the prevention of prostate cancer, " the authors compose. " They take on suggest, however, that character certain humankind subgroups there was an association between adjunct intake and suffering risks of prostate cancer. "
Impact an accompanying editorial, I - Min Shelter, Sc. D., of Brigham and Male ' s Hospital juice Boston, Mass., and colleagues discuss the implications of Hayes and colleagues ' study mastery the understanding of earlier studies of vitamin E supplementation and cancer risk. The editorialists recognize that the study impact complete not indulge well-made agency for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data keep up unclear about the benefits of vitamin E supplementation for prostate cancer prevention guidance the general tribe; however, know onions are well-built data supporting tropical cessation to shorten cancer incidence. The authors dash off, " Now and supremacy the unfolding, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an heavy course of occupation for overall cancer prevention is to project efforts to stop the initiation of blazing and to popularize the cessation of ardent among those who effect come off. "
