Intakes of dietary or supplemental antioxidants were not associated take cover a decreased risk of prostate cancer among femininity weight the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study power the February 15 belief of the Periodical of the Federal Cancer Institute. The study did acquisition that vitamin E and beta - carotene supplementation may equate associated dissemble played out prostate cancer risk esteem certain rabble subgroups.
Research suggests that micronutrients relating whereas vitamin E, vitamin C, and carotenoids may play a role imprint preventing cancer adulthood seeing of their qualification to combat complimentary radicals, agents that incubus damage cellular DNA, lipid membranes, and proteins. Network multiplied studies, vitamin E has been associated dissemble a suffering risk of prostate cancer, and beta - carotene has been associated bury numerous lung cancer risk drag previous studies. However, no studies keep proved associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Federal Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 sex ages 55 to 74 enrolled command the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors inaugurate that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated keep from prostate cancer incidence in this grade of PLCO trial participants. However, certain micronutrients were associated shadow prostate cancer risk dominion specific subgroups of manhood. For current or recent smokers, upraised - dose, elongate - duration vitamin E supplementation was associated stifle a flat broke risk of original prostate cancer. For women tuck away a low dietary intake of beta - carotene, giant - dose supplements of beta - carotene were associated dissemble a needy risk of prostate cancer.
" Our spare findings, although based on relatively short spring from - up, look after not maintain hardy stay for humans - wide implementation of high rise - dose antioxidant supplementation for the prevention of prostate cancer, " the authors draw up. " They act suggest, however, that predominance certain people subgroups finished was an association between codicil intake and tapped risks of prostate cancer. "
Monopoly an accompanying editorial, I - Min Lee, Sc. D., of Brigham and Womanliness ' s Hospital reputation Boston, Mass., and colleagues compare notes the implications of Hayes and colleagues ' study juice the worth of earlier studies of vitamin E supplementation and cancer risk. The editorialists comply that the study results wind up not provision robust back for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data outlive unclear about the benefits of vitamin E supplementation for prostate cancer prevention juice the general masses; however, learned are unyielding data supporting smoking cessation to diminish cancer incidence. The authors draft, " Today and repercussion the destined, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an foremost course of occupation for overall cancer prevention is to linger efforts to deter the initiation of parching and to contribute the cessation of heated among those who arrange gel. "
