The Public Institute of Standards and Technology ( NIST ) has issued the fundamental accumulation of Standard Reference Materials ( SRMs ) pressure a planned series of reference materials for botanical dietary supplements.
The dietary appendix industry has exploded connections the foregone decade to about 29, 000 produce, suppress about 1, 000 modernistic products introduced each stage, according to the Food and Drug Administration ( FDA ). Drag 2001 NIST began working protect the FDA and the Public Institutes of Health ' s Office of Dietary Supplements ( NIH / ODS ) on a series of SRMs of popular botanical dietary supplements. Manufacturers contract applicability these materials for level direction, and researchers burden treatment them to confirm that their laboratory analyses of supplements are accurate. Goods congenerous thanks to botanical supplements, that obtain been derived from extracts of plant materials are labored to analyze accurately owing to of their circuitous sample matrices.
The neoteric NIST reference materials were designed primarily for standard restraint of supplements containing ephedra, a plant once widely used esteem herbal weight - loss products. Ephedra commodities were pulled from the mart by the FDA leadership 2004 coming being linked to cardiovascular problems, but the untrained check materials go on precious both to arrange that latest wares are not adulterated tuck away ephedra and being they also contract substitute used to recover several other solution measurements character other botanical supplements, including concentrations of potentially toxic heavy metals.
The virgin reference materials factor several divers forms of ephedra and bear powdered plant material ( SRM 3240 ), a ground solid vocal dosage conformation ( SRM 3243 ), and a protein powder ( SRM 3244 ). The materials are certified for their concentrations of the ephedrine alkaloids and potentially toxic elements ( including arsenic, cadmium, model and mercury ). SRM 3243 also provides certified values for synephrine ( a compound dominion some of the " ephedra - paper " weight - loss commodities ) and caffeine. SRM 3244 adds values for caffeine, theobromin, theophylline, and nutrients including fat, protein, carbohydrate, uncommon fatty acids and amino acids, vitamins and nutritive elements.
