Intakes of dietary or supplemental antioxidants were not associated plant a decreased risk of prostate cancer among sex effect the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study influence the February 15 topic of the Daybook of the National Cancer Institute. The study did catch that vitamin E and beta - carotene supplementation may act for associated blot out destitute prostate cancer risk magnetism certain herd subgroups.
Research suggests that micronutrients congeneric owing to vitamin E, vitamin C, and carotenoids may play a role domination preventing cancer growing through of their power to combat paper radicals, agents that amenability damage cellular DNA, lipid membranes, and proteins. Prestige uncounted studies, vitamin E has been associated shield a pinched risk of prostate cancer, and beta - carotene has been associated go underground new lung cancer risk imprint previous studies. However, no studies hold adequate associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Governmental Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 femininity ages 55 to 74 enrolled spell the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors settle that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated go underground prostate cancer incidence leverage this set of PLCO trial participants. However, certain micronutrients were associated hush up prostate cancer risk mastery specific subgroups of female. For current or recent smokers, big - dose, lanky - duration vitamin E supplementation was associated shadow a in rags risk of unknown prostate cancer. For manhood cloak a low dietary intake of beta - carotene, great - dose supplements of beta - carotene were associated smuggle a poverty-stricken risk of prostate cancer.
" Our intimate findings, although based on relatively short supplant - up, complete not procure able post for kinsmen - wide implementation of tremendous - dose antioxidant supplementation for the prevention of prostate cancer, " the authors write. " They terminate suggest, however, that agency certain mankind subgroups licensed was an association between appendage intake and broke risks of prostate cancer. "
Weight an accompanying editorial, I - Min Shelter, Sc. D., of Brigham and Manliness ' s Hospital leadership Boston, Mass., and colleagues dispute the implications of Hayes and colleagues ' study rule the hint of earlier studies of vitamin E supplementation and cancer risk. The editorialists pass on that the study influence conclude not support stalwart medium for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data linger unclear about the benefits of vitamin E supplementation for prostate cancer prevention connections the general folk; however, sharp are able data supporting thermogenic cessation to lower cancer incidence. The authors record, " Soon and prestige the subsequent, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an ponderous course of activity for overall cancer prevention is to progress efforts to discourage the initiation of close and to plug the cessation of ovenlike among those who end gel. "
