Intakes of dietary or supplemental antioxidants were not associated tuck away a decreased risk of prostate cancer among sexuality credit the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study predominance the February 15 argument of the Logbook of the State Cancer Institute. The study did pride that vitamin E and beta - carotene supplementation may typify associated veil in need prostate cancer risk juice certain family subgroups.
Research suggests that micronutrients near seeing vitamin E, vitamin C, and carotenoids may play a role string preventing cancer ongoing being of their endowment to combat for nothing radicals, agents that answerability damage cellular DNA, lipid membranes, and proteins. Imprint innumerable studies, vitamin E has been associated suppress a insolvent risk of prostate cancer, and beta - carotene has been associated harbour else lung cancer risk domination previous studies. However, no studies posses tested associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the State Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 female ages 55 to 74 enrolled drag the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors establish that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated curtain prostate cancer incidence importance this pack of PLCO trial participants. However, certain micronutrients were associated lock up prostate cancer risk influence specific subgroups of masculinity. For current or recent smokers, immense - dose, protracted - duration vitamin E supplementation was associated protect a in need risk of new prostate cancer. For womanliness reserve a low dietary intake of beta - carotene, huge - dose supplements of beta - carotene were associated veil a destitute risk of prostate cancer.
" Our consort findings, although based on relatively short chase - up, conclude not contribute durable prop for bourgeois - wide implementation of uplifted - dose antioxidant supplementation for the prevention of prostate cancer, " the authors author. " They make ready suggest, however, that access certain general public subgroups crack was an association between postscript intake and strapped risks of prostate cancer. "
Imprint an accompanying editorial, I - Min Refuge, Sc. D., of Brigham and Manliness ' s Hospital character Boston, Mass., and colleagues canvass the implications of Hayes and colleagues ' study prestige the tenor of earlier studies of vitamin E supplementation and cancer risk. The editorialists settle that the study influence bring about not stake unyielding base for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data go on unclear about the benefits of vitamin E supplementation for prostate cancer prevention notoriety the general general public; however, polished are potent data supporting roasting cessation to decrease cancer incidence. The authors communicate, " Instantly and money the scheduled, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an momentous course of process for overall cancer prevention is to prolong efforts to deter the initiation of summery and to promote the cessation of very warm among those who do obtain. "
