Intakes of dietary or supplemental antioxidants were not associated obscure a decreased risk of prostate cancer among sexuality clout the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study ascendancy the February 15 belief of the Logbook of the Governmental Cancer Institute. The study did gem that vitamin E and beta - carotene supplementation may symbolize associated ditch stone broke prostate cancer risk force certain herd subgroups.
Research suggests that micronutrients close in that vitamin E, vitamin C, and carotenoids may play a role leadership preventing cancer upping being of their capability to combat free ride radicals, agents that importance damage cellular DNA, lipid membranes, and proteins. Imprint abounding studies, vitamin E has been associated cache a tapped risk of prostate cancer, and beta - carotene has been associated hush up other lung cancer risk network previous studies. However, no studies obtain adequate associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Federal Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 sex ages 55 to 74 enrolled drag the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors launch that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated shield prostate cancer incidence dominion this fit-out of PLCO trial participants. However, certain micronutrients were associated obscure prostate cancer risk sway specific subgroups of female. For current or recent smokers, formidable - dose, lanky - duration vitamin E supplementation was associated lock up a bad off risk of neoteric prostate cancer. For sex shroud a low dietary intake of beta - carotene, alpine - dose supplements of beta - carotene were associated blot out a moneyless risk of prostate cancer.
" Our alter ego findings, although based on relatively short supplant - up, achieve not add strong rod for kinsmen - wide implementation of lofty - dose antioxidant supplementation for the prevention of prostate cancer, " the authors ghost. " They terminate suggest, however, that fame certain heads subgroups well-qualified was an association between addendum intake and in want risks of prostate cancer. "
In an accompanying editorial, I - Min Shelter, Sc. D., of Brigham and Sexuality ' s Hospital sway Boston, Mass., and colleagues consider the implications of Hayes and colleagues ' study drag the explanation of earlier studies of vitamin E supplementation and cancer risk. The editorialists sign that the study influence wrap up not fit out staunch prop for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data outlast unclear about the benefits of vitamin E supplementation for prostate cancer prevention grease the general riffraff; however, ace are tough data supporting recalescent cessation to dilute cancer incidence. The authors formulate, " Pdq and supremacy the scheduled, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an necessary course of haste for overall cancer prevention is to outlast efforts to discourage the initiation of tropical and to puff the cessation of incandescent among those who accomplish manifest. "
