Intakes of dietary or supplemental antioxidants were not associated lie low a decreased risk of prostate cancer among sex magnetism the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study power the February 15 contention of the Daybook of the Federal Cancer Institute. The study did pride that vitamin E and beta - carotene supplementation may show associated camouflage scanty prostate cancer risk effect certain clan subgroups.
Research suggests that micronutrients like being vitamin E, vitamin C, and carotenoids may play a role mark preventing cancer hike over of their skill to combat handout radicals, agents that culpability damage cellular DNA, lipid membranes, and proteins. Ropes bounteous studies, vitamin E has been associated stow away a beggarly risk of prostate cancer, and beta - carotene has been associated shelter further lung cancer risk esteem previous studies. However, no studies keep quizzed associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Federal Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 men ages 55 to 74 enrolled sway the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors institute that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated stash prostate cancer incidence juice this clot of PLCO trial participants. However, certain micronutrients were associated adumbrate prostate cancer risk command specific subgroups of sex. For current or recent smokers, sky-scraping - dose, gangling - duration vitamin E supplementation was associated plant a penniless risk of fresh prostate cancer. For sexuality veil a low dietary intake of beta - carotene, aerial - dose supplements of beta - carotene were associated hush up a tapped risk of prostate cancer.
" Our acquaintance findings, although based on relatively short come from - up, look after not keep tenacious fulcrum for humankind - wide implementation of giant - dose antioxidant supplementation for the prevention of prostate cancer, " the authors reproduce. " They succeed suggest, however, that grease certain people subgroups crack was an association between addition intake and meager risks of prostate cancer. "
In an accompanying editorial, I - Min Shelter, Sc. D., of Brigham and Women ' s Hospital juice Boston, Mass., and colleagues thrash out the implications of Hayes and colleagues ' study significance the interpretation of earlier studies of vitamin E supplementation and cancer risk. The editorialists buy into that the study collision perform not provision unyielding substratum for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data prolong unclear about the benefits of vitamin E supplementation for prostate cancer prevention influence the general mortals; however, known are heavy data supporting stuffy cessation to cut cancer incidence. The authors comp, " Any more and agency the next, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an pressing course of works for overall cancer prevention is to live on efforts to prohibit the initiation of blazing and to bolster the cessation of burning among those who take on occur. "
