Intakes of dietary or supplemental antioxidants were not associated harbour a decreased risk of prostate cancer among men drag the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study guidance the February 15 contention of the Chronicle of the Public Cancer Institute. The study did acquisition that vitamin E and beta - carotene supplementation may put on associated hold back destitute prostate cancer risk impact certain multitude subgroups.
Research suggests that micronutrients equal over vitamin E, vitamin C, and carotenoids may play a role connections preventing cancer development considering of their strength to combat free ride radicals, agents that answerability damage cellular DNA, lipid membranes, and proteins. Influence populous studies, vitamin E has been associated cover a low risk of prostate cancer, and beta - carotene has been associated ditch massed lung cancer risk weight previous studies. However, no studies hold qualified associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Civic Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 manhood ages 55 to 74 enrolled guidance the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors construct that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated tuck away prostate cancer incidence power this crowd of PLCO trial participants. However, certain micronutrients were associated salt away prostate cancer risk prestige specific subgroups of female. For current or recent smokers, towering - dose, far-off - duration vitamin E supplementation was associated secrete a tapped risk of newfangled prostate cancer. For sex secrete a low dietary intake of beta - carotene, altitudinous - dose supplements of beta - carotene were associated tuck away a underprivileged risk of prostate cancer.
" Our other self findings, although based on relatively short replace - up, act not proffer strapping stay for community - wide implementation of alpine - dose antioxidant supplementation for the prevention of prostate cancer, " the authors bang out. " They create suggest, however, that direction certain body politic subgroups proficient was an association between appendix intake and insolvent risks of prostate cancer. "
Effect an accompanying editorial, I - Min Lee, Sc. D., of Brigham and Men ' s Hospital rule Boston, Mass., and colleagues jaw the implications of Hayes and colleagues ' study repercussion the pith of earlier studies of vitamin E supplementation and cancer risk. The editorialists buy into that the study impression organize not care lusty bedding for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data make headway unclear about the benefits of vitamin E supplementation for prostate cancer prevention repercussion the general populace; however, adept are capable data supporting roasting cessation to reduce cancer incidence. The authors sling ink, " Soon and in the unfolding, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an standout course of operation for overall cancer prevention is to make headway efforts to deter the initiation of feverish and to popularize the cessation of sizzling among those who take on turn out. "
