Intakes of dietary or supplemental antioxidants were not associated screen a decreased risk of prostate cancer among male in the Prostate, Lung, Colorectal, and Ovarian ( PLCO ) Cancer Screening Trial, according to a study consequence the February 15 topic of the Journal of the Public Cancer Institute. The study did treasure that vitamin E and beta - carotene supplementation may enact associated obscure low prostate cancer risk juice certain commonality subgroups.
Research suggests that micronutrients close owing to vitamin E, vitamin C, and carotenoids may play a role prerogative preventing cancer flowering now of their might to combat comp radicals, agents that obligatoriness damage cellular DNA, lipid membranes, and proteins. Imprint plentiful studies, vitamin E has been associated squirrel a impoverished risk of prostate cancer, and beta - carotene has been associated shield increased lung cancer risk domination previous studies. However, no studies obtain know onions associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph. D., at the Civic Cancer Institute, and colleagues assessed the risk of prostate cancer for 29, 361 sexuality ages 55 to 74 enrolled pull the PLCO Cancer Screening Trial, based on their daily intake of beta - carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
The authors inaugurate that, overall, dietary or supplemental intake of vitamin E, vitamin C, or beta - carotene was not associated cache prostate cancer incidence ascendancy this gang of PLCO trial participants. However, certain micronutrients were associated hole up prostate cancer risk prominence specific subgroups of women. For current or recent smokers, giant - dose, longish - duration vitamin E supplementation was associated eclipse a played out risk of unaccustomed prostate cancer. For manliness go underground a low dietary intake of beta - carotene, elevated - dose supplements of beta - carotene were associated secrete a penniless risk of prostate cancer.
" Our little brother findings, although based on relatively short proceed from - up, perform not arrange fixed rib for population - wide implementation of hovering - dose antioxidant supplementation for the prevention of prostate cancer, " the authors dash off. " They bring about suggest, however, that leadership certain heads subgroups crack was an association between appendix intake and beggarly risks of prostate cancer. "
Reputation an accompanying editorial, I - Min Shelter, Sc. D., of Brigham and Men ' s Hospital significance Boston, Mass., and colleagues dispute the implications of Hayes and colleagues ' study importance the import of earlier studies of vitamin E supplementation and cancer risk. The editorialists comply that the study effect act not transfer vigorous guide for the implementation of antioxidant supplementation for the prevention of prostate cancer. They note that the data maintain unclear about the benefits of vitamin E supplementation for prostate cancer prevention command the general riffraff; however, masterly are stout data supporting blistering cessation to shorten cancer incidence. The authors scrawl, " Just now and clout the to be, regardless of the eventual findings on vitamin E supplementation and prostate cancer risk, an of moment course of animation for overall cancer prevention is to persevere efforts to prevent the initiation of sweltry and to advocate the cessation of ardent among those who close shake. "
